2022 North Dakota St Football Schedule
| Sep 3 | Drake Fargo, N.D. | W 56-14 | ||
| Sep 10 | North Carolina A&T Fargo, N.D. | W 43-3 | ||
| Sep 17 | @Arizona Tucson, AZ | L 28-31 | ||
| Sep 24 |  | @South Dakota Vermillion, S.D. | W 34-17 | |
| Oct 1 | Youngstown St Fargo, N.D. | W 27-14 | ||
| Oct 8 | @Indiana St Terre Haute, Ind. | W 31-26 | ||
| Oct 15 | South Dakota St Fargo, N.D. | L 21-23 | ||
| Oct 29 | Illinois St Fargo, N.D. | W 24-7 | ||
| Nov 5 | @Western Illinois Macomb, Ill. | W 56-17 | ||
| Nov 12 |  | @Southern Illinois Carbondale, IL | W 21-18 | |
| Nov 19 |  | North Dakota Fargo, N.D. | W 42-21 | |
| Dec 3 | Montana Fargo, ND | W 49-26 | ||
| Dec 9 | Samford Fargo, ND | W 27-9 | ||
| Dec 16 | Incarnate Word Fargo, ND | W 35-32 | ||
| Jan 8 | South Dakota St Frisco, Texas | L 21-45 | ||
| Jan 8 | @South Dakota St Frisco, Texas | L 21-45 |