2022 Michigan State Mens Hockey Schedule
| Oct 1 | 7:00 ET | USNTDP | L 3-4 | |
| Oct 7 | 7:00 ET |  | Bowling Green | L 1-3 |
| Oct 8 | 7:07 ET | | @Bowling Green | W 2-1 |
| Oct 13 | 7:00 ET |  | Mass.-Lowell | W 4-3 |
| Oct 14 | 7:30 ET | | Mass.-Lowell | L 2-3 |
| Oct 21 | 7:00 ET | LIU | W 3-1 | |
| Oct 22 | 6:00 ET | LIU | W 8-4 | |
| Oct 28 | 7:30 ET |  | @Notre Dame | L 0-5 |
| Oct 29 | 6:00 ET | | @Notre Dame | T 1-1 |
| Nov 4 | 7:00 ET |  | Wisconsin | W 5-0 |
| Nov 5 | 6:00 ET | | Wisconsin | W 5-1 |
| Nov 10 | 7:00 ET |  | Ohio State | W 4-2 |
| Nov 11 | 7:00 ET | | Ohio State | W 4-3 |
| Nov 18 | 7:00 ET |  | @Penn State | L 3-4 |
| Nov 19 | 7:30 ET | | @Penn State | W 7-3 |
| Nov 25 | 7:05 ET |  | @Miami | W 5-3 |
| Nov 26 | 5:05 ET | | @Miami | W 4-0 |
| Dec 2 | 6:30 ET |  | Minnesota | L 0-5 |
| Dec 3 | 6:00 ET | | Minnesota | L 3-6 |
| Dec 9 | 6:30 ET |  | Michigan | W 2-1 |
| Dec 10 | 6:30 ET | | @Michigan | L 1-2 |
| Dec 27 | 7:00 ET |  | Ferris State | L 2-4 |
| Dec 28 | 3:30/7:00 ET | Mich Tech/WMU | ||
| Dec 28 | 3:30 ET |  | Michigan Tech | L 2-3 |
| Jan 6 | 7:00 ET | | @Ohio State | L 1-3 |
| Jan 7 | 4:00 ET | | @Ohio State | L 0-6 |
| Jan 13 | 7:00 ET | | Penn State | W 3-2 |
| Jan 14 | 7:00 ET | | Penn State | T 4-4 |
| Jan 27 | 7:00 CT | | @Minnesota | L 0-8 |
| Jan 28 | 4:00 CT | | @Minnesota | L 3-6 |
| Feb 3 | 7:00 ET | | Notre Dame | W 3-0 |
| Feb 4 | 4:00 ET | | Notre Dame | W 3-2 |
| Feb 10 | 7:00 ET | | Michigan | L 2-4 |
| Feb 11 | 8:00 ET | | @Michigan | L 3-4 |
| Feb 17 | 8:00 CT | | @Wisconsin | W 6-2 |
| Feb 18 | 7:00 CT | | @Wisconsin | L 2-6 |
| Mar 3 | 7:00 ET | | @Notre Dame | L 0-1 |
| Mar 4 | 4:30 ET | | @Notre Dame | W 4-2 |
| Mar 5 | 6:00 ET | | @Notre Dame | W 4-2 |
| Mar 11 | 8:00 CT | | @Minnesota | L 1-5 |