2022 Penn State Mens Hockey Schedule
| Oct 7 | 7:00 ET |  | Canisius | W 5-2 |
| Oct 8 | 6:00 ET | | Canisius | W 7-5 |
| Oct 13 | 7:00 ET |  | Mercyhurst | W 6-3 |
| Oct 14 | 7:05 ET | | @Mercyhurst | W 4-1 |
| Oct 20 | 7:00 ET | St. Thomas | W 6-2 | |
| Oct 21 | 7:00 ET | St. Thomas | W 3-2 | |
| Oct 22 | St. Thomas | |||
| Oct 28 | 7:00 CT |  | @Wisconsin | W 2-1 |
| Oct 29 | 7:00 CT | | @Wisconsin | W 4-0 |
| Nov 4 | 8:00 ET |  | Michigan | W 3-0 |
| Nov 5 | 7:30 ET | | Michigan | L 3-4 |
| Nov 10 | 7:00 CT |  | @Minnesota | W 4-2 |
| Nov 11 | 7:00 CT | | @Minnesota | L 1-3 |
| Nov 18 | 7:00 ET |  | Michigan State | W 4-3 |
| Nov 19 | 7:30 ET | | Michigan State | L 3-7 |
| Nov 22 | 7:00 ET |  | Alaska | W 3-2 |
| Nov 23 | 5:00 ET | | Alaska | W 2-1 |
| Dec 2 | 7:00 ET |  | Ohio State | W 2-1 |
| Dec 3 | 5:30 ET | | Ohio State | L 3-4 |
| Dec 9 | 7:00 ET |  | @Notre Dame | W 5-2 |
| Dec 10 | 6:00 ET | | @Notre Dame | L 3-5 |
| Dec 30 | 5:05 ET |  | @RIT | W 6-1 |
| Dec 31 | 5:30 ET | | RIT | W 3-1 |
| Jan 13 | 7:00 ET | | @Michigan State | L 2-3 |
| Jan 14 | 7:00 ET | | @Michigan State | T 4-4 |
| Jan 20 | 7:00 ET | | Notre Dame | L 1-2 |
| Jan 21 | 5:00 ET | | Notre Dame | W 3-2 |
| Jan 27 | 7:00 ET | | @Michigan | L 3-7 |
| Jan 28 | 7:00 ET | | @Michigan | L 4-5 |
| Feb 3 | 7:00 ET | | @Ohio State | W 4-3 |
| Feb 4 | 6:30 ET | | @Ohio State | L 2-4 |
| Feb 17 | 6:30 ET | | Minnesota | L 2-7 |
| Feb 18 | 6:30 ET | | Minnesota | L 2-3 |
| Feb 24 | 7:00 ET | | Wisconsin | W 6-1 |
| Feb 25 | 5:00 ET | | Wisconsin | L 1-2 |
| Mar 3 | 7:00 ET | | @Ohio State | L 1-5 |
| Mar 4 | 5:00 ET | | @Ohio State | W 2-1 |
| Mar 5 | 5:00 ET | | @Ohio State | L 1-3 |
| Mar 24 | 5:00 ET |  | Michigan Tech | W 8-0 |
| Mar 26 | 6:30 ET | @Colgate/Michigan | ||
| Mar 26 | 6:30 ET | | @Michigan |