2022 Mass.-Lowell Mens Hockey Schedule
| Oct 1 | 6:05 ET |  | St. Lawrence | W 4-0 |
| Oct 7 | 7:15 ET |  | Miami | L 1-3 |
| Oct 8 | 6:05 ET | | Miami | W 4-2 |
| Oct 13 | 7:00 ET |  | @Michigan State | L 3-4 |
| Oct 14 | 7:30 ET | | @Michigan State | W 3-2 |
| Oct 22 | 7:00 ET |  | @Northeastern | W 3-2 |
| Oct 28 | 7:15 ET |  | Boston University | W 2-1 |
| Oct 29 | 7:00 ET | | @Boston University | L 1-2 |
| Nov 4 | 7:15 ET |  | Vermont | W 4-0 |
| Nov 5 | 6:05 ET | | Vermont | W 2-0 |
| Nov 15 | 7:00 ET |  | @Boston College | L 2-3 |
| Nov 18 | 7:15 ET |  | Connecticut | W 3-2 |
| Nov 19 | 3:35 ET | | @Connecticut | L 2-4 |
| Nov 25 | 7:00 |  | Massachusetts | L 1-2 |
| Nov 26 | 3:00/7:00 GMT | Quinnipiac/Dart | ||
| Nov 26 | 3:00 GMT |  | @Dartmouth | W 4-3 |
| Dec 3 | 7:00 ET | | @Massachusetts | T 1-1 |
| Dec 9 | 7:00 ET | | @Dartmouth | W 3-2 |
| Dec 30 | 6:05 ET | Alaska Anchorage | L 2-4 | |
| Dec 31 | 4:05 ET | Alaska Anchorage | L 2-3 | |
| Jan 7 | 1:05 ET |  | @American Int'l | W 4-2 |
| Jan 13 | 7:00 ET |  | @Maine | W 2-1 |
| Jan 14 | 7:00 ET | | @Maine | L 3-5 |
| Jan 20 | 7:15 ET |  | New Hampshire | W 6-2 |
| Jan 21 | 7:00 ET | | @New Hampshire | W 3-2 |
| Jan 27 | 7:15 ET | | Massachusetts | W 1-0 |
| Feb 3 | 7:15 ET | | Boston College | T 2-2 |
| Feb 4 | 6:05 ET | | New Hampshire | L 4-5 |
| Feb 12 | 2:05 ET | | Maine | T 1-1 |
| Feb 17 | 7:00 ET |  | @Providence | L 2-3 |
| Feb 18 | 6:05 ET | | Providence | W 2-1 |
| Feb 24 | 7:15 ET |  | Merrimack | L 3-5 |
| Feb 25 | 7:00 ET | | @Merrimack | L 0-2 |
| Mar 3 | 7:15 ET | | Northeastern | W 3-1 |
| Mar 4 | 7:00 ET | | @Northeastern | L 3-7 |
| Mar 11 | 4:00 ET | | @Connecticut | W 2-1 |
| Mar 17 | 7:30 ET | | @Merrimack | L 1-2 |