2021 Massachusetts Mens Hockey Schedule
| Oct 2 | 7:30 ET |  | MSU-Mankato | L 0-2 |
| Oct 3 | 4:00 ET | | MSU-Mankato | L 3-6 |
| Oct 15 | 7:05 ET |  | @American Int'l | W 5-1 |
| Oct 16 | 7:00 ET | | American Int'l | W 4-2 |
| Oct 23 | 7:00 ET |  | Dartmouth | L 2-3 |
| Oct 29 | 7:00 ET |  | @Merrimack | W 2-1 |
| Oct 30 | 7:00 ET | | Merrimack | W 5-4 |
| Nov 5 | 7:00 ET |  | Providence | W 1-0 |
| Nov 6 | 7:00 ET | | @Providence | W 5-1 |
| Nov 12 | 7:30 ET |  | @Boston University | T 2-2 |
| Nov 13 | 7:00 ET | | Boston University | L 3-4 |
| Nov 19 | 7:00 ET |  | New Hampshire | W 3-0 |
| Nov 20 | 7:00 ET | | @New Hampshire | L 1-2 |
| Dec 3 | 7:15 ET | @UMass Lowell | T 4-4 | |
| Dec 3 | 7:15 ET |  | @Mass.-Lowell | T 4-4 |
| Dec 4 | 7:00 ET | UMass Lowell | W 3-2 | |
| Dec 4 | 7:00 ET | | Mass.-Lowell | W 3-2 |
| Dec 9 | 7:00 ET | | @Merrimack | W 3-2 |
| Dec 31 | PPD |  | @Union | |
| Jan 1 | PPD | | @Union | |
| Jan 3 | 6:00 ET | | Merrimack | W 4-3 |
| Jan 8 | 5:00 ET |  | @Michigan | L 1-4 |
| Jan 9 | 4:00 ET | | @Michigan | L 2-4 |
| Jan 21 | 7:00 ET |  | Northeastern | W 3-2 |
| Jan 22 | 7:30 ET | | @Northeastern | W 6-0 |
| Jan 25 | 7:00 ET | | Boston University | L 4-6 |
| Jan 28 | 7:00 ET | | Providence | L 1-2 |
| Jan 30 | 1:05 ET | @UMass Lowell | ||
| Jan 30 | 1:05 ET | | @Mass.-Lowell | W 4-3 |
| Feb 4 | 7:00 ET | LIU | W 6-3 | |
| Feb 5 | 7:00 ET | LIU | W 3-1 | |
| Feb 11 | 7:00 ET |  | Maine | L 2-3 |
| Feb 12 | 7:00 ET | | Maine | W 4-2 |
| Feb 18 | 7:05 ET |  | @Connecticut | W 2-1 |
| Feb 19 | 7:00 ET | | Connecticut | L 2-4 |
| Feb 25 | 7:05 ET |  | @Vermont | W 5-1 |
| Feb 26 | 7:05 ET | | @Vermont | W 8-2 |
| Mar 4 | 7:00 ET |  | @Boston College | L 1-2 |
| Mar 5 | 7:00 ET | | Boston College | L 3-4 |
| Mar 12 | 7:00 ET | TBD | ||
| Mar 12 | 7:00 ET | | Providence | W 4-2 |
| Mar 18 | 7:30 ET | | Mass.-Lowell | W 3-1 |
| Mar 19 | 7:00 ET | | Connecticut | W 2-1 |
| Mar 25 | 6:00 ET |  | @Minnesota | L 3-4 |