2021 Quinnipiac Mens Hockey Schedule
| Oct 2 | 4:30 ET |  | Maine | W 7-0 |
| Oct 8 | 4:30 ET |  | @Boston College | T 2-2 |
| Oct 9 | 4:30 ET |  | @Northeastern | W 3-0 |
| Oct 16 | 7:05 ET |  | @Vermont | W 2-0 |
| Oct 22 | 7:00 ET |  | North Dakota | W 5-2 |
| Oct 23 | 7:00 ET | | North Dakota | L 1-3 |
| Oct 26 | 7:00 ET |  | Holy Cross | W 5-2 |
| Oct 29 | 7:05 ET |  | @American Int'l | T 2-2 |
| Oct 30 | 7:00 ET | | American Int'l | W 2-1 |
| Nov 5 | 7:00 ET |  | @Yale | W 3-0 |
| Nov 6 | 4:00 ET |  | @Brown | W 1-0 |
| Nov 12 | 7:00 ET | Arizona State | W 5-3 | |
| Nov 13 | 7:00 ET | Arizona State | W 5-2 | |
| Nov 19 | 7:00 ET |  | Clarkson | T 2-2 |
| Nov 20 | 7:00 ET |  | St. Lawrence | W 8-0 |
| Dec 3 | 7:00 ET |  | @Rensselaer | W 2-0 |
| Dec 4 | 7:00 ET |  | @Union | W 4-0 |
| Dec 10 | 7:45 ET | @LIU | W 4-1 | |
| Dec 11 | 7:00 ET | LIU | W 5-0 | |
| Jan 2 | 4:00 ET |  | Princeton | |
| Jan 3 | 7:00 ET | | @Princeton | |
| Jan 7 | PPD | | Brown | |
| Jan 8 | PPD | | Yale | |
| Jan 14 | 7:00 ET |  | Harvard | W 3-0 |
| Jan 15 | 7:00 ET |  | Dartmouth | |
| Jan 16 | 5:00 ET | | Dartmouth | W 3-1 |
| Jan 18 | 7:00 ET | | Princeton | W 9-0 |
| Jan 21 | 7:00 ET |  | @Colgate | W 5-1 |
| Jan 22 | 7:00 ET |  | @Cornell | L 1-2 |
| Jan 26 | 7:00 ET | | @Princeton | W 6-0 |
| Jan 28 | 7:00 ET | | @Princeton | |
| Jan 29 | 7:00 ET |  | @Sacred Heart | W 3-2 |
| Jan 30 | 1:00/4:30 ET | UConn/Yale | ||
| Jan 30 | 4:30 ET |  | Connecticut | W 2-0 |
| Feb 4 | 7:00 ET | | Union | W 2-1 |
| Feb 5 | 7:00 ET | | Rensselaer | W 1-0 |
| Feb 8 | 7:00 ET | | Brown | W 4-1 |
| Feb 11 | 7:00 ET | | @St. Lawrence | W 3-1 |
| Feb 12 | 7:00 ET | | @Clarkson | L 1-3 |
| Feb 18 | 7:00 ET | | @Dartmouth | W 5-0 |
| Feb 19 | 7:00 ET | | @Harvard | L 0-1 |
| Feb 22 | 7:00 ET | | Yale | W 4-0 |
| Feb 25 | 7:00 ET | | Cornell | L 0-1 |
| Feb 26 | 7:00 ET | | Colgate | W 4-0 |
| Mar 11 | 7:00 ET | TBD | ||
| Mar 11 | 7:00 ET | | St. Lawrence | W 4-1 |
| Mar 12 | 7:00 ET | TBD | ||
| Mar 12 | 7:00 ET | | St. Lawrence | W 4-3 |
| Mar 18 | 4:00 ET | | Colgate | W 3-1 |
| Mar 19 | 7:30 ET | Harvard/Clarkson | ||
| Mar 19 | 7:30 ET | | Harvard | L 2-3 |
| Mar 25 | 8:00 ET |  | St Cloud St | W 5-4 |
| Mar 27 | 6:30 ET |  | @Michigan | L 4-7 |