2025 South Dakota St Football Schedule
| Aug 30 | Sacramento St Brookings, S.D. | |||
| Sep 6 | @Montana St Bozeman, Mont. | |||
| Sep 13 | Drake Brookings, S.D. | |||
| Sep 27 | Mercyhurst Brookings, S.D. | |||
| Oct 4 | @Youngstown St Youngstown, Ohio | |||
| Oct 11 | Northern Iowa Brookings, S.D. | |||
| Oct 18 | @Murray St Murray, Ky. | |||
| Oct 25 | North Dakota St Brookings, SD | |||
| Nov 1 | Indiana St Brookings, SD | |||
| Nov 8 |  | @South Dakota Vermillion, SD | ||
| Nov 15 | Illinois St Brookings, SD | |||
| Nov 22 |  | @North Dakota Grand Forks, N.D. |