2021 Clarkson Mens Hockey Schedule
| Oct 2 | 7:00 ET |  | St. Lawrence | L 0-3 |
| Oct 8 | 7:07 AT |  | @Alaska | W 2-1 |
| Oct 9 | 7:07 AT | | @Alaska | L 1-2 |
| Oct 19 | 7:00 ET |  | Canisius | T 4-4 |
| Oct 22 | 7:00 ET | | Alaska | W 5-1 |
| Oct 23 | 7:00 ET | | Alaska | W 4-2 |
| Oct 29 | 7:00 ET |  | Michigan Tech | L 0-3 |
| Oct 30 | 7:30 ET | | Michigan Tech | W 2-1 |
| Nov 5 | 7:00 ET |  | @Union | L 3-4 |
| Nov 6 | 7:00 ET |  | @Rensselaer | L 1-3 |
| Nov 12 | 7:00 ET |  | Harvard | W 6-2 |
| Nov 13 | 7:00 ET |  | Dartmouth | W 3-0 |
| Nov 19 | 7:00 ET |  | @Quinnipiac | T 2-2 |
| Nov 20 | 7:00 ET |  | @Princeton | W 8-3 |
| Nov 26 | 7:07 CT |  | @Wisconsin | T 1-1 |
| Nov 27 | 6:00 CT | | @Wisconsin | W 3-0 |
| Dec 3 | 7:00 ET |  | Cornell | |
| Dec 3 | 7:00 ET |  | Colgate | W 2-1 |
| Dec 4 | 7:00 ET | | Colgate | |
| Dec 4 | 7:00 ET | | Cornell | T 4-4 |
| Dec 10 | 7:05 MT | @Arizona State | L 3-4 | |
| Dec 11 | 7:05 MT | @Arizona State | L 1-4 | |
| Jan 3 | PPD | | @Canisius | |
| Jan 7 | CANC |  | @Merrimack | |
| Jan 8 | 7:30 ET |  | @New Hampshire | L 1-5 |
| Jan 14 | 7:00 ET | | Rensselaer | |
| Jan 15 | 7:00 ET | | Union | W 8-2 |
| Jan 16 | 5:00 ET | | Rensselaer | W 5-0 |
| Jan 21 | 7:00 ET | | @Dartmouth | T 5-5 |
| Jan 22 | 7:00 ET | | @Harvard | W 4-3 |
| Jan 28 | 7:00 ET | | St. Lawrence | W 1-0 |
| Jan 29 | 7:00 ET | | @St. Lawrence | T 4-4 |
| Feb 4 | 7:00 ET |  | @Brown | W 5-0 |
| Feb 5 | 7:00 ET |  | @Yale | W 3-2 |
| Feb 11 | 7:00 ET | | Princeton | W 7-1 |
| Feb 12 | 7:00 ET | | Quinnipiac | W 3-1 |
| Feb 18 | 7:00 ET | | @Colgate | W 4-1 |
| Feb 19 | 7:00 ET | | @Cornell | L 2-6 |
| Feb 25 | 7:00 ET | | Yale | L 2-3 |
| Feb 26 | 7:00 ET | | Brown | W 4-0 |
| Mar 11 | 7:00 ET | TBD | ||
| Mar 11 | 7:00 ET | | Union | W 3-2 |
| Mar 12 | 7:00 ET | TBD | ||
| Mar 12 | 7:00 ET | | Union | W 4-3 |
| Mar 18 | 7:30 ET | | Harvard | L 3-5 |