2021 Colgate Mens Hockey Schedule
| Oct 2 | 7:05 ET |  | @RIT | W 5-2 |
| Oct 8 | 7:05 ET |  | @Vermont | W 5-3 |
| Oct 9 | 7:05 ET | | @Vermont | W 2-1 |
| Oct 15 | 7:00 ET |  | Merrimack | W 2-1 |
| Oct 16 | 4:00 ET | | Merrimack | L 3-5 |
| Oct 22 | 7:00 ET | Arizona State | W 8-3 | |
| Oct 23 | 7:00 ET | Arizona State | L 3-4 | |
| Oct 29 | 7:00 ET |  | Western Michigan | L 5-6 |
| Oct 30 | 5:00 ET | | Western Michigan | L 1-2 |
| Nov 5 | 5:00 ET |  | @Dartmouth | L 2-3 |
| Nov 6 | 7:00 ET |  | @Harvard | L 1-5 |
| Nov 12 | 7:00 ET |  | Rensselaer | W 5-2 |
| Nov 13 | 3:00 ET |  | Union | L 0-2 |
| Nov 19 | 7:30 ET |  | Yale | W 3-0 |
| Nov 20 | 7:30 ET |  | Brown | W 6-0 |
| Nov 27 | 7:00 ET |  | @Connecticut | L 1-6 |
| Dec 3 | 7:00 ET |  | @St. Lawrence | |
| Dec 3 | 7:00 ET |  | @Clarkson | L 1-2 |
| Dec 4 | 7:00 ET | | @Clarkson | |
| Dec 4 | 7:00 ET | | @St. Lawrence | L 3-4 |
| Jan 7 | 6:37 ET |  | @Northern Michigan | L 2-4 |
| Jan 8 | 6:37 ET | | @Northern Michigan | L 3-6 |
| Jan 14 | PPD | | @Brown | |
| Jan 15 | 7:00 ET | | @Yale | |
| Jan 16 | 7:00 ET | | @Yale | T 2-2 |
| Jan 21 | 7:00 ET |  | Quinnipiac | L 1-5 |
| Jan 22 | 7:00 ET |  | Princeton | T 2-2 |
| Jan 28 | 7:00 ET | | Harvard | L 3-5 |
| Jan 29 | 7:00 ET | | Dartmouth | W 2-1 |
| Feb 4 | 7:30 ET |  | Cornell | W 3-2 |
| Feb 5 | 7:00 ET | | @Cornell | T 2-2 |
| Feb 11 | 7:00 ET | | @Union | W 6-4 |
| Feb 12 | 7:00 ET | | @Rensselaer | W 3-2 |
| Feb 14 | 5:00 ET | | @Brown | T 1-1 |
| Feb 18 | 7:00 ET | | Clarkson | L 1-4 |
| Feb 19 | 7:00 ET | | St. Lawrence | W 4-2 |
| Feb 25 | 7:00 ET | | @Princeton | W 4-3 |
| Feb 26 | 7:00 ET | | @Quinnipiac | L 0-4 |
| Mar 4 | 7:00 ET | | Yale | W 3-2 |
| Mar 5 | 7:00 ET | | Yale | W 5-1 |
| Mar 11 | 7:00 ET | | @Cornell | L 1-3 |
| Mar 12 | 7:00 ET | | @Cornell | W 4-2 |
| Mar 13 | 4:00 ET | | @Cornell | W 2-1 |
| Mar 18 | 4:00 ET | | @Quinnipiac | L 1-3 |