2021 Maine Mens Hockey Schedule
| Oct 2 | 4:30 ET |  | @Quinnipiac | L 0-7 |
| Oct 8 | 7:07 CT |  | @Nebraska-Omaha | L 1-4 |
| Oct 9 | 6:07 CT | | @Nebraska-Omaha | L 3-5 |
| Oct 22 | 7:30 ET |  | Sacred Heart | L 0-1 |
| Oct 23 | 5:00 ET | | Sacred Heart | T 3-3 |
| Oct 29 | 7:00 ET |  | @Northeastern | L 0-5 |
| Oct 30 | 7:00 ET | | @Northeastern | L 2-3 |
| Nov 5 | 7:30 ET |  | Connecticut | L 3-4 |
| Nov 6 | 7:00 ET | | Connecticut | L 2-3 |
| Nov 12 | 7:30 ET |  | Merrimack | W 6-5 |
| Nov 13 | 5:00 ET | | Merrimack | L 0-2 |
| Nov 18 | 7:00 ET |  | @Boston College | L 2-6 |
| Nov 19 | 7:00 ET | | @Boston College | T 2-2 |
| Nov 27 | 5:00 ET | UMass Lowell | L 0-2 | |
| Nov 27 | 5:00 ET |  | Mass.-Lowell | L 0-2 |
| Dec 3 | 7:30 ET |  | Vermont | L 0-1 |
| Dec 4 | 7:00 ET | | Vermont | T 1-1 |
| Dec 10 | 7:30 ET |  | Union | T 1-1 |
| Dec 11 | 5:00 ET | | Union | W 4-3 |
| Dec 31 | CANC |  | @Penn State | |
| Jan 1 | CANC | | @Penn State | |
| Jan 7 | 7:30 ET |  | Alaska | L 2-6 |
| Jan 8 | 7:00 ET | | Alaska | W 4-2 |
| Jan 14 | 7:15 ET | @UMass Lowell | ||
| Jan 14 | 7:15 ET | | @Mass.-Lowell | L 3-5 |
| Jan 15 | 6:05 ET | @UMass Lowell | ||
| Jan 15 | 6:05 ET | | @Mass.-Lowell | L 3-4 |
| Jan 28 | 7:30 ET | | Boston College | W 4-1 |
| Feb 4 | 7:30 ET |  | @Boston University | L 0-4 |
| Feb 5 | 7:00 ET | | @Merrimack | L 0-5 |
| Feb 11 | 7:00 ET |  | @Massachusetts | W 3-2 |
| Feb 12 | 7:00 ET | | @Massachusetts | L 2-4 |
| Feb 18 | 7:00 ET |  | New Hampshire | W 6-3 |
| Feb 19 | 7:00 ET | | New Hampshire | L 2-5 |
| Feb 25 | 7:00 ET |  | @Providence | L 2-4 |
| Feb 26 | 4:00 ET | | @Providence | L 2-3 |
| Mar 4 | 7:30 ET | | Boston University | L 1-5 |
| Mar 5 | 7:00 ET | | Boston University | W 8-1 |
| Mar 9 | 7:00 ET | | @Merrimack | L 2-6 |